Table 1. Selection of FIV vaccine strains

Table 1. Selection of FIV vaccine strains.

Acute immune alteration Homologous
protection
vaccine^a

FIV isolate FIV
subtype Blood
virus load CD4
decrease CD4/CD8
inversion Clinical
disease cell virus

Shizuoka (SHI) D + None None None Yes Yes

Petaluma (PET) A ++ Slight/none None None Yes Yes

Swiss Z2 (Z2)^b A +++ Slight/none None None ? ?

Millan 2 (M2) B ++++ Moderate ? ? Yes No

Amsterdam 19 (AM19)^b A ++++ ? ? ? No ?

Utrecht 113 (UT113)^b A ++++ ? ? ? No ?

Bangston (BANG) Agag/Benv ++++ Moderate Moderate None No? No

Glasgow 8 (GL8)^b A +++++ Major Major Major No No

^aSource of the homologous protection results are from reviews (11, 14).
^bAcute immune alteration and blood virus load are based on in vitro-derived inocula. Remaining strains are based on in vivo-derived inocula.


			Acute immune alteration			Homologous protection vaccine^a

FIV isolate	FIV subtype	Blood virus load	CD4 decrease	CD4/CD8 inversion	Clinical disease	cell	virus

Shizuoka (SHI)	D	+	None	None	None	Yes	Yes
Petaluma (PET)	A	++	Slight/none	None	None	Yes	Yes
Swiss Z2 (Z2)^b	A	+++	Slight/none	None	None	?	?
Millan 2 (M2)	B	++++	Moderate	?	?	Yes	No
Amsterdam 19 (AM19)^b	A	++++	?	?	?	No	?
Utrecht 113 (UT113)^b	A	++++	?	?	?	No	?
Bangston (BANG)	Agag/Benv	++++	Moderate	Moderate	None	No?	No
Glasgow 8 (GL8)^b	A	+++++	Major	Major	Major	No	No