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May 9, 2008

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Vol. 3, No. 7, 18 April 2003

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From Science:
Recruitment of HIV and its receptors to dendritic cell-T cell junctions
Dendritic cell-T cell contact may facilitate transmission of HIV by locally concentrating virus, receptor and coreceptor during the formation of an infectious synapse.

— By Thomas J. Hope et al.

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Broad and potent anti-HIV responses by DNA priming and boosting with protein-adsorbed polylactide coglycolide microparticles
Gag DNA was the most potent technology for CTL induction, while Gag protein adsorbed to PLG microparticles was best for antibody and helper-T-cell responses. These results suggested possible synergy between the DNA and Gag-PLG vaccine technologies for providing strong and broad immune responses. Journal of Virology 77(10), 6087.

From Medscape: U.S. CDC initiative for HIV prevention: An interview with Harold W. Jaffe
How will this program improve recognition and treatment of HIV infection among those who currently do not realize they are infected? (one-time registration required)

From people to places: focusing AIDS prevention efforts where it matters most
Despite the current attention given to controlling the AIDS epidemic in sub-Saharan Africa through treatment, there exists an equally urgent need to improve prevention efforts. AIDS 17(6), 895, 2003

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