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AIDScience Perspective: Vaccine research: Anti-R7V antibodies may protect some HIV-infected patients from developing AIDS: A conversation with Jean-Claude Chermann [Full text article] [About AIDScience articles]  [See recent AIDScience articles] [dEbates: Submit a response to this article]

Hot News: Sexual behaviors in an urban bathhouse 15 years into the HIV epidemic. Well into the HIV epidemic, bathhouses remain venues for ongoing spread of HIV and opportunities for intervention. Journal of Acquired Immune Deficiency Syndromes 30(5), 522, 2002 [Read abstract] Related commentary the CDC HIV/STD/TB Prevention News Update: [Read commentary]

Study: HIV clinics do not give consistent information on safe sex, HIV status disclosure to patients. HIV clinics differed substantially in the percentage of patients who reported that they received prevention messages from clinic staff. AIDS 16(14), 1953, 27 September 2002 [Read abstract] Related commentary from KaiserNetwork.org: [Read commentary]

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. The small group of HIV-infected people who receive no treatment and yet show no signs of illness for years appear to have increased proliferative capacity of HIV-specific CD8+ T cells linked to enhanced effector function, than most clinical progressors who cannot control the virus. Nature Immunology, published online 7 October 2002: [Read abstract] (free registration required) Related National Institute of Allergy and Infectious Diseases (NIAID) release: [Read NIAID release]

Natural resistance to HIV: HIV-specific IgA is present in HIV-exposed, persistently seronegative (HEPS) individuals and neutralizes primary strains of HIV-1 in vitro. IgA exclusively bound an epitope within gp41 corresponding to the leucine zip motif in the alpha-helical region. AIDS 16(13), 1731, 6 September 2002 [Read abstract] Related article: Journal of Acquired Immune Deficiency Syndromes 30(4), 413, 1 August 2002 [Read abstract]

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