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From Science: The identity of the CD8 antiviral factor (CAF), a soluble factor secreted by CD8 T lymphocytes from certain HIV-1-infected individuals who are immunologically stable, has been elusive since its discovery in 1986. A New York team claims to have found the culprits. Contribution of human a-defensin-1, -2 and -3 to the anti-HIV-1 activity of CD8 antiviral factor By Linqi Zhang et al. [Free full text article] [About AIDScience articles]  [See recent AIDScience articles] [See other Science articles] [dEbates: Submit a response to this article]

But other researchers who have been digging for the anti-HIV factor and have seen the new data say they're not throwing away their shovels. Mystery anti-HIV factor unmasked? By Jon Cohen [Free full text article] [About AIDScience articles]  [See recent AIDScience articles] [See other Cohen articles] [dEbates: Submit a response to this article]

Hot News: More evidence the spermicide nonoxynol-9 could cause toxic effects enhancing HIV-1 infection. The study did not show a protective effect of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in high-risk women. The Lancet 360, 917, 28 September 2002 [Read full report (free)]

Trends in sexual risk behaviors among high school students—United States, 1991-2001. To examine changes in sexual risk behavior that occurred among high school students in the United States during 1991-2001, the U.S. CDC analyzed data from six national Youth Risk Behavior surveys. Morbidity and Mortality Weekly Report 51(38), 856, 27 September 2002 [Read report]

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