Other Issues:

AIDScience Perspective: With several products moving into late-stage clinical trials (and one phase III trial already completed), the microbicides field is accumulating valuable experience working with women at high risk for HIV—experience that also offers important lessons for vaccines: Learning from microbicides: A young field's experience working with high-risk women by Emily Bass, from the IAVI Report. [Full text article]  [About AIDScience articles]  [See recent AIDScience articles] [dEbates: Submit a response to this article]

Hot News: A new vaccine candidate generated neutralizing antibodies that are not type-specific. Structures consisting of covalently crosslinked complexes of soluble human CD4 (shCD4) and HIV-1IIIB envelope glycoproteins (gp120 or gp140) were able to generate antibodies in rhesus macaques that neutralized a wide range of primary HIV-1 isolates regardless of the coreceptor usage or genetic subtype. Proc. Natl. Acad. Sci. USA, published online before print August 21, 2002 [Read abstract] Commentary about the paper in the Institute of Human Virology's Web site [Go to site]

Unrecognized HIV infection, risk behaviors, and perceptions of risk among young black men who have sex with men (BMSM). Data from the CDC's Young Men's Survey (YMS) were used to evaluate the prevalence of unrecognized HIV infection, barriers to testing, and reasons for nonuse of condoms among BMSM aged 15-22 years. The findings in this report are consistent with previous studies suggesting that in several U.S. cities, the majority of young HIV-infected MSM, particularly BMSM, were unaware of their infection. Morbidity and Mortality Weekly Report 51(33), 733, 23 August 2002 [Read report]

HIV prevention research: Cumulative knowledge or accumulating studies? The U.S. CDC HIV/AIDS Prevention Research Synthesis (PRS) project found over 4000 studies related to the prevention of HIV infection. The Journal of Acquired Immune Deficiency Syndromes has published a supplement comprising articles from the PRS project. The project claims to be the largest research review conducted to date of the effectiveness of interventions to reduce HIV risk behavior. Journal of Acquired Immune Deficiency Syndromes 30(Supplement 1), 1 July 2002 [Go to journal] Or, go to Journal Headlines to click on individual article links: [This month's Journal Headlines]

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