Other Issues:

AIDScience Perspective: From Science: HIV/AIDS MEETING: Tough challenges ahead on political and scientific fronts by Jon Cohen. [Full text article]  [About AIDScience articles]  [See recent AIDScience articles] [See other Cohen articles]  [dEbates: Submit a response to this article]

Hot News: Superinfection: another problem for HIV vaccine design. Two cases of human HIV-1 intersubtype superinfection were detected by molecular and serologic analyses several weeks after complete seroconversion to the primary infection with a strain belonging to a different subtype. Superinfection occurred despite specific T cell and humoral antibody responses to the primary virus. Journal of Virology 76(15), 7444, August 2002 [Read abstract]

HIV-specific CD8+ T cells in human breast milk. Breast milk contains HIV-specific major histocompatibility complex class I-restricted CD8+ CTLs. Their presence suggests a role in limiting transmission and could shed light on the rationale for vaccine strategies. Journal of Virology 76(15), 7365, August 2002 [Read abstract]

AIDS Conference: New anti-HIV microbicides. A topical microbicide containing a non-nucleoside reverse transcriptase inhibitor (Dapivirine) blocked vaginal transmission of HIV-1 in a hu-SCID mice model. Another novel candidate is a polymer derived from sulfuric acid treatment of mandelic acid or SAMMA, which has broad inhibitory activity against HIV and HSV with little or no cytotoxicity. AIDS 2002 Conference, abstract WeOrD1314 [Read abstract] AIDS 2002 Conference, abstract WeOrD1315 [Read abstract]

From Medscape: HAART and prevention of HIV transmission. A wide-ranging report on the potential role of antiretroviral therapy in HIV prevention, based on 11 expert reviews. Medscape HIV/AIDS 8(2) 2002 [Read report] (requires free registration)

Science Special Issue: HIV/AIDS: Therapies, vaccines, challenges Special suite of news, commentary, and review articles covering the state of AIDS vaccine and therapy research, to mark the AIDS 2002 Conference in Barcelona: [Read articles]

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