Other Issues:

AIDScience Perspective: An issue with serious implications for both HIV prevention and vaccine development: Research has confirmed what many gay men and HIV prevention workers have known for a while: the practice of intentional unsafe sex is becoming more common. Paradigm shift for HIV prevention in the United States by Gordon Mansergh, from the Division of HIV/AIDS Prevention, U.S. CDC.  [Full text article]  [About AIDScience articles]  [See recent AIDScience articles]  [dEbates: Submit a response to this article]

Science Classic Papers: HIV changes to hide from immune detection. The fact that HIV is an astounding escape artist has now been confirmed at a population level. This is worrying news for long-term immune control of HIV infection and for vaccine development. Science's Compass: HLA leaves its footprints on HIV Science 296(5572), 1410, 24 May 2002. [Free full-text article] Research Article: Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level Science 296(5572), 1439, 24 May 2002. [Free full-text article] [Other Science Classic Papers]

Hot News: New HIV reservoir detected in HAART patients. A subset of non-T cells with NK markers are persistently infected and suggest that HIV infection of NK cells is important for virus persistence. Proc. Natl. Acad. Sci. USA 99(10), 7015 (2002) [Read abstract]

Another crack in the code? Unstimulated CD8+ T lymphocytes from HIV-exposed-uninfected individuals inhibit HIV-1. CD8+ T cells from exposed-uninfected (EU) individuals exert a strong, broad-spectrum HIV-suppressive activity, suggesting a role of non-cytotoxic antiviral mechanisms in resistance to HIV-1 infection. AIDS 16(7), 1003 (2002) [Read abstract]

From Medscape: Protease inhibitor combination therapy and decreased condom use among gay men. Among men who had sex with men, treatment with protease inhibitors was associated with never using condoms and with inconsistent use of condoms. See Medscape link (free one time registration required). Southern Medical Journal 95(4), 421 (2002) [Read article]

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